Visible marks and white or dark lines on the nail that often appear one to two months after chemotherapy starts.

Grooves that run horizontally across the nails. The nails can change color to yellow. Caused when therapy interrupts nail growth.

This is due to damage to the nail matrix and thinning, and can be very painful when split nails catch on things or break off.

Low white blood cell count (neutropenia) can cause skin infections around & under the nails - causing redness, swelling, tenderness, and sometimes pus.

This painful side effect of therapy often appears as dark brown or purple bruising under the nail bed.

A loosened connection between the nail and the nail bed, causing white or opaque areas. This can be painful and lead to infection as bacteria enters the gap under the nail bed.

Without proper treatment, partial or total nail loss can occur -- increasing the risk of infection and making daily tasks, such as buttoning clothes or wearing shoes, very difficult.

A concave, spoon-like appearance to the nail shape or texture that occurs when treatment affects normal nail growth.